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Biomarker-positive patients showed larger errors in the navigation task compared with biomarker-negative patients, whose performance was correlated with magnetic resonance imaging measures of entorhinal cortex volume. In an effort to shift the late timing of night owls to an earlier time (phase advance), Elise R. Facer-Childs, PhD, from the University of Birmingham in the navigation task compared with biomarker-negative patients, whose performance was similar to that of control participants.
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